hyperferritinemia: Symptoms, causes, and herbal tea treatment

The ferritin level refers to the protein that essentially stores iron in the body. Hyperferritinemia is most often found in patients as a result of iron overload, infection, inflammation, or malignancy. Excess iron in the body, as indicated by high blood ferritin levels, can affect our health. However, it is possible to slow down the absorption of this trace element by making the right food choices.

Definition hyperferritinemia herbal tea treatment

Hyperferritinemia is a condition of excessive ferritin in the body. Ferritin is a protein involved in storing iron because it can bind to iron. Excessive ferritin is a sign of iron overload disease (such as hemochromatosis). Regardless of whether it is related to another disease, methrinemia can lead to a serious complication: cataracts. Mutations in the ferritin-light chain (FTL) gene can cause this rare disease, called methemoferrinemia-cataract syndrome.

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Symptoms hyperferritinemia herbal tea treatment

The signs and symptoms of iron overload disorder are often mild, and a 2019 source trusted Source reports that in 3 out of 4 cases, people with iron overload show no symptoms. Signs usually trusted Source do not appear until middle age or, in females, after menopause. Nowadays, people with hemochromatosis are less likely to develop symptoms because diagnosis tends to take place earlier than it did in the past.

If the condition advances, the main symptoms include:

  • tiredness or fatigue
  • weakness
  • weight loss
  • abdominal pain
  • high blood sugar levels
  • hyperpigmentation, or the skin turning a bronze color
  • a loss of libido, or sex drive
  • in males, a reduction in the size of the testicles
  • in females, reduced or absent menstruation

time going, the following conditions may develop:

  • arthritis
  • liver disease or cirrhosis (permanent scarring) of the liver
  • enlargement of the liver
  • diabetes
  • hypothyroidism
  • heart disease
  • pancreatitis

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Causes hyperferritinemia herbal tea treatment

Hemochromatosis is a genetic disease that causes hyperabsorption of iron by the intestines and therefore a high level of ferritin. There are many causes of hyperferritinemia:

  • an excessively meaty diet,
  • excessive intake of alcohol, mainly red wine,
  • the presence of tumors (liver, lung, pancreas, kidney or breast),
  • Hodgkin’s lymphoma or acute leukemia,
  • an infectious or inflammatory syndrome (e.g. polyarthritis),
  • viral or acute hepatitis.

A weak liver or regular blood transfusions are also risk factors for developing hemochromatosis, and high ferritin levels are common after menopause.

Risk Factors hyperferritinemia herbal tea treatment

The following risk factors may increase a person’s likelihood of having hemochromatosis:

  • Genetic factors: Having two copies of a faulty HFE gene is the main risk factor for hereditary hemochromatosis. The person inherits one copy of the mutated HFE gene from each parent. H refers to high, and FE means iron.
  • Family history: A person with a parent, child, brother, or sister with hemochromatosis is more likely to have it.
  • Ethnicity: According to the NHLBITrusted Source, Caucasian people of Northern European descent have a higher risk of having the HFE gene mutation and of developing hemochromatosis. They note that it is less common in people of African American, Hispanic, Asian, and American Indian descent.
  • Gender: Iron overload affects both males and females, although it may have a less significant effect trusted Source on females. The reason for this is that most females regularly lose blood during menstruation, and blood loss reduces iron levels. Males may develop symptoms at the age of about 40–60 years trusted Source, and females may have symptoms after menopause.

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Consequences hyperferritinemia herbal tea treatment

When its level is within the normal range, iron is an anti-oxidant. On the other hand, when it is present in excess in the blood, iron becomes a pro-oxidant that will accelerate the degeneration of tissues. This excess iron will also affect various organs, particularly the liver, heart, and endocrine glands. Finally, it can cause heart weakness, joint problems or liver damage, and even liver cancer.

High ferritin levels can also be the cause of many diseases, such as neurodegenerative diseases (Alzheimer’s, Parkinson’s), obesity, acute mononucleosis, etc. It also increases the risk of developing type II diabetes (7 times higher risk).

Complications hyperferritinemia herbal tea treatment

Without treatment, an accumulation of iron can lead to health complications, such as:

  • cirrhosis
  • a higher chance of liver cancer relating to cirrhosis or hemochromatosis
  • diabetes and associated complications
  • congestive heart failure if too much iron builds up in the heart and the body cannot circulate enough blood
  • irregular heart rhythms, or arrhythmias, leading to chest pain, palpitations, and dizziness
  • endocrine problems, such as hypothyroidism or hypogonadism
  • arthritis, osteoarthritis, or osteoporosis
  • bronze or gray skin due to the deposits of iron in skin cells

Other complications can include depression, gallbladder disease, and some cancers. According to the Iron Disorders Institute, some autopsies have revealed that people with neurodegenerative diseases — such as Alzheimer’s disease, multiple sclerosis, and epilepsy — had problems with iron levels in the brain.

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 Low iron diet hyperferritinemia herbal tea treatment

The low iron diet for hemochromatosis aims to favor plant proteins that are sources of non-haem iron and to incorporate foods that reduce the absorption of iron in the body. The aim is to maintain an optimal nutritional status despite the nutritional changes imposed by this diet.

Plant proteins

Although there is no consensus on this subject, it seems obvious that the consumption of plant proteins is to be favored as part of the low iron diet for hemochromatosis. Plant proteins are sources of non-haem iron which is much less well absorbed by the body than the iron contained in animal products. Proteins are essential for the body, so it is important to continue to have an adequate intake.

The best sources of non-haem iron are: Pulses, Tofu, Oilseeds, Eggs, Tea, and coffee
Drinking tea and coffee with meals reduces iron absorption because of the amount of tannins they contain. This is even more true for tea, which contains more liver-healthy antioxidants and less caffeine than coffee. This makes tea a great beverage to include with meals as part of the hemochromatosis diet.

Fibre-rich foods

Foods rich in dietary fiber contain phytates and oxalates. Phytates form insoluble complexes with iron, reducing their absorption. Oxalates also reduce the absorption of iron in the body.

Calcium

Calcium interferes with and reduces the absorption of iron. In the case of a special hemochromatosis diet, it is therefore recommended that a source of calcium be included in every meal. Food sources of calcium to combat hemochromatosis are: Milk, Cheese, Yoghurt, Sardines, and salmon, Tofu
Soy milk and other calcium-enriched plant milks

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Natural treatment hyperferritinemia herbal tea treatment

Camelia Sinensis

Certainly, the most interesting plant because it contains, among other things, catechin, also known as epigallocatechin gallate. It is one of the most powerful antioxidants, it opposes cell aging and the effects of excess iron. Its tannic action chelates iron; there is thus anemia in tea drinkers due to this chelation which prevents the resorption of dietary iron. In addition, it has a slimming effect, which reduces other vascular risks such as high cholesterol or high blood sugar levels.

Hamamelis virginiana

The leaves and bark of this plant contain about ten percent tannins, substances to which the astringent, anti-inflammatory, and hemostatic effects of the plant are attributed: proanthocyanidins, catechins, and, in particular, hamamelitanine. Its anti-inflammatory action and its effect on the vascular walls make it a plant of choice in the treatment of disorders linked to hyperferritinemia

OPC (grape seed extract)

Grape seed extract contains more than 95% proanthocyanidins, whose role in inflammatory processes is due to their high bioavailability and affinity for collagen. It is one of the most powerful antioxidants available.

Rosmarinus officinalis

Rosemary is rich in essential oil, tannin, and rosmarinic acid. The combination of the antioxidant action of rosmarinic acid, certain flavonoids (diosmin), and tannins makes it a valuable plant in the treatment of inflammation. Tannins are substances of organic origin that are found in practically all parts (leaves, roots, bark) of most plants. Tannins are derivatives of gallic acid and other polyphenolic acids. These compounds precipitate iron in the intestine and prevent its resorption in the body. They also have an antioxidant and « cell rejuvenating » action, which justifies the properties of wine taken in moderate quantities (cardiovascular protection). In addition to this effect, it has a choleretic and cholagogue action that favors digestion. To treat excess iron naturally, the natural treatment will require a complementary therapeutic reflection on the associated factors as well as the causes of this hyperferritinemia.

An adequate therapy will ensure the control of a multifactorial situation.

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