Rokitansky Syndrome: Major Things you need to know & herbal Tea Treatment

par admin · Publié 10 septembre 2021 · Mis à jour 5 mai 2023

MRKH syndrome is the common name for Mayer-Rokitansky-Küster-Hauser syndrome. Rokitansky syndrome constitutes the second most common cause of primary amenorrhea, after gonadal dysgenesis. MRKH syndrome is a condition where young women are born either without a vagina and uterus or with an underdeveloped vagina and uterus. It is the most common type of vaginal agenesis. Agenesis is Latin for « not developed. » Therefore vaginal agenesis means the vagina is not developed. Treatment of this syndrome should be multidisciplinary and individualized to the patient. It includes a combination of psychosocial support and correction of the anatomic abnormality. MRKH affects at least one in 4500 women. MRKH syndrome was first described in 1829. However, historical evidence of the condition dates back to 460 B.C.

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Definition

Aplasia means that the uterus and vagina have incomplete development. Syndrome means a set of signs and symptoms that characterize a disease. This syndrome affects one in 4,500 girls and is the most common cause of vaginal absence associated with uterine malformations.

Girls with this syndrome are generally healthy; they have a female phenotype (i.e. normal morphological features), the karyotype is normal 46XX. To date, genetic studies have not identified a gene responsible for all MRKH syndromes. The typical form is characterized by isolated uterovaginal aplasia. External genitalia (vulva) is normal, breast development and hair growth are normal. The ovaries have normal functions. This syndrome is congenital as it occurs before birth, during pregnancy when certain developmental abnormalities may occur. Uterovaginal aplasia can also be associated with other malformations: the most frequent are renal anomalies affecting about 1/3 of people. These are most often the absence of a kidney (unilateral agenesis) or a kidney in an unusual position (ectopia), these anomalies having no repercussions on the function of the kidney or kidneys. Bone anomalies affect 10 to 15% of people, affecting the vertebrae (scoliosis) and the extremities (hands, forearms). This can be referred to as the MURCS syndrome (uterovaginal aplasia, renal anomaly, and skeletal anomalies). Less common are hearing abnormalities (4-10%), cardiovascular abnormalities (1%), and even rarer are abnormalities of ovarian function.

Keywords

Dilation, Mayer-Rokitansky-Küster-Hauser syndrome, müllerian aplasia, vaginal agenesis, vaginoplasty, MRKH syndrome, Amenorrhea, Laparoscopic Davydov-Moore vaginoplasty, Congenital absence of the uterus and vagina (CAUV), Genital renal ear syndrome (GRES), MRKH syndrome, Mullerian agenesis, Mullerian dysgenesis, Rokitansky Kuster Hauser syndrome, Rokitansky syndrome, Transition, Transition care, Rare disease, Systematic literature review

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Causes Rokitansky Syndrome Herbal Treatment

The cause of MRKH syndrome is unknown. Changes in several genes that are involved in development before birth have been identified in females with MRKH syndrome. However, each has been found in only a few affected individuals, and it is unclear whether these changes cause MRKH syndrome. Researchers are working to determine how genetic changes might lead to problems with reproductive system development in females.

The reproductive abnormalities of MRKH syndrome are due to the incomplete development of the Müllerian duct. This structure in the embryo develops into the uterus, fallopian tubes, cervix, and the upper part of the vagina. The cause of the abnormal development of the Müllerian duct in affected individuals is unknown. Originally, researchers suspected that MRKH syndrome was caused by environmental factors during pregnancy, such as medication or maternal illness. However, subsequent studies have not identified an association with any specific maternal drug use, illness, or another factor. Researchers now suggest that in combination, genetic and environmental factors contribute to the development of MRKH syndrome, although the specific factors are often unknown.

It is also unclear why some affected individuals have abnormalities in parts of the body other than the reproductive system. Certain tissues and organs, such as the kidneys, develop from the same embryonic tissue as the Müllerian duct, and researchers suspect that problems during development could affect these organs as well.

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Consequences Rokitansky Syndrome Herbal Treatment

The consequences of this syndrome are of two different kinds: Impact on sexual life and Psychological difficulties

Impact on sexual life

Sexual life is complicated or impossible, even if the hormones and secondary sexual characteristics are preserved. These difficulties, combined with an absence of pregnancy plans, have important psychological consequences.

Psychological difficulties

Psychological difficulties at puberty with alteration of the body schema in girls affected by this syndrome, of self-esteem, presence of gender identity conflicts, anxiety about love life and subsequent marriage.

This is why the diagnosis must be evoked and confirmed progressively in order to prepare the young girl and her parents for this possibility and the subsequent consequences of this syndrome. This medical and psychological care will be carried out by a multidisciplinary team with a general practitioner or paediatrician, the gynaecologist, a psychologist and a specialist opinion on this syndrome.

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Transmission Methods Rokitansky Syndrome Herbal Treatment

Its genetic mode of transmission is still poorly defined, even if family forms have been described and lead to the suspicion that the syndrome is genetic, but associated with a change in the expression of the defective gene during intrauterine life due to environmental factors. The use of a drug against nausea and vomiting during pregnancy, distilbene, would have favoured this modification of the expression of this gene without this being formally proven. This drug was withdrawn from the market in the mid-1970s because of the observation of these gynaecological malformations in girls and young women whose mothers had taken Distilbene. The drug is believed to have had an impact on the DNA of these children, altering this potentially defective gene.

Diagnosis Rokitansky Syndrome Herbal Treatment

MRKH syndrome is most often diagnosed when a young woman fails to get her menstrual period. If an exam is performed at that time, the doctor will likely discover the lack of a fully formed vagina and uterus. Further diagnosis might then include MRI, ultrasound, or laparoscopic surgery. These more thorough tests can help diagnose other organ systems affected by MRKH. They can also determine whether women with MRKH have functioning ovarian tissue. Usually, one or more tests will be used to characterize MRKH syndrome after it has been identified during a physical exam.

Natural Treatment with herbs and roots

Considering the fact that no disease is to be neglected, all treatments furthermore the effective ones have to be taken into consideration. We have already work on it and find a very natural Rokitansky Syndrome herbal treatment. The fact that it is natural, prevent you from every secondary effect and complication. All are natural, 100% natural.

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Rokitansky Syndrome: Major Things you need to know & herbal Tea Treatment

Causes Rokitansky Syndrome Herbal Treatment

Consequences Rokitansky Syndrome Herbal Treatment

Impact on sexual life

Psychological difficulties

Transmission Methods Rokitansky Syndrome Herbal Treatment

Diagnosis Rokitansky Syndrome Herbal Treatment

Natural Treatment with herbs and roots

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